aK-Pur Bridge Grant
The “aK-Pur” project is dealing with knowledge transfer in advanced purification of colloidal solutions of atelocollagen for pharmaceutical and bio-medical applications, in order to optimize the current technology applied to S.C. Sanimed International Impex S.R.L., and to improve the skills of personnel involved in the manufacturing of collagen porous substrates for the class III sterile medical devices, at the aforementioned company. The transfer consists in: (i) the assessment of current technology, (ii) technology redesign, and (iii) changing the purification step through the replacement of the dialysis operation by tangential flow diafiltration through porous cartridges. In addition, new manufacturing regulations, and a system of training of personnel involved in the whole technological flow will be developed.
The project will benefit from the facilities and logistics of three research centers from the "Gheorghe Asachi" Technical University of Iasi, as well as from those of the "Research infrastructure for collagen products” and the “Research centre and innovative services in advanced biotechnologies", currently in place at Sanimed company. Services and facilities provided by all five mentioned centers are detailed on the ERRIS platform.
The project team includes four members of the faculty staff as senior researchers, and two master students, who will improve their practical training. The total value of the anticipated expenditure of the project is of 450,000 lei, of which 49% staff costs, 30% for materials and reagents, 5% third-party services, 4% to mobilities, and 12% overheads.
Expected effects after project completion meet the company's demands for increased process yields and product quality, but also for human resource with improved skills and competencies in collagen processing.
Technology optimization and training in advanced purification processes of collagen for pharmaceutical and biomedical applications,
at S.C. Sanimed International Impex S.R.L.